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2048 Ventures

New York, New York · Invests in US; North America · Website

Pre-SeedSeedAI & Machine LearningDeveloper ToolsHealthcare & BiotechRoboticsHardware & DevicesFrontier TechDeveloper Tools & InfrastructureBiotech & Life SciencesHealthcare & Digital HealthRobotics & Automation

Thesis

Thesis-driven early-stage venture capital firm investing in visionary founders building transformative technologies in Vertical AI, Deep Tech, Healthcare, and Biotech. Focus on companies built on defensible data moats and novel technological breakthroughs solving fundamental problems. Emphasis on long-term value creation and partnership from day zero. Rapid decision-making (10-15 business days) combined with hands-on operational support. NPS score of 100 from portfolio founders.

Likely not a fit for

Companies outside four core verticals. Pure consumer applications without technical defensibility or data moats. Late-stage companies (Series C+) except strategic follow-ons. Founder teams lacking clear vision and conviction.

How they invest

Lead or follow
Usually leads
Typical decision
~2 weeks
Warm intro
Not required
Involvement
Takes a board seat
Fund status
Actively deploying
Decision process
Partnership vote

Partners & team

10 contacts on file

AI

Alex Iskold

General PartnerFounder and Partner · Primary contact

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a•••@gm•••.com

LinkedIn profile

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ZA

Zann Ali

PartnerPartner

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z•••@20•••.vc

LinkedIn profile

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JW

Julie Wolf

PartnerPartner

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j•••@20•••.vc

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DC

Daniella Cohen

PrincipalPrincipal

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SP

Sandra Pérez Baos

AssociateSenior Associate

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EJ

Edward Jin

AssociateAssociate

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LI

Lilly Iskold

AssociateAnalyst

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AI

Alice Iskold

AssociateAnalyst

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JM

Justine Marchand

Platform & OpsVP of Finance & Operations

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CJ

Colette Jumbert

Platform & OpsOperations Associate

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Portfolio

PsyrinHealthcare Digital

Psyrin combines expertise in AI, neuroscience, and clinical practice to build solutions for every dimension of mental health assessment and care, focusing on improving operational efficiency and patient outcomes.

AerodomeSecurity Cyber

Aerodome provides a fully automated air support system utilizing drones for public safety, enabling rapid response to emergency incidents with minimal human intervention.

GlossGeniusEnterprise Software

GlossGenius is an all-in-one software solution designed for salon, spa, and medspa businesses, offering features such as online booking, client management, payment processing, and AI-driven growth analytics.

Soona

Soona is an all-in-one creative platform for e-commerce, specializing in photo and video content. The company enhances its offerings with generative AI tools acquired from Mokker.ai, aiming to make the internet more beautiful through e-commerce brands.

VitallyEnterprise Software

Vitally provides a platform designed to enhance customer success through productivity tools, AI-driven insights, and collaborative features tailored for customer success teams.

Tangram VisionEnterprise Software

Tangram Vision specializes in calibration solutions for robotics and automation, providing industry-leading software that ensures optimal performance of cameras and sensors.

WarecloudsLogistics Supply Chain

Wareclouds offers distributed logistics solutions for large brands, focusing on same-day delivery and community-based dark stores throughout Chile. They aim to enhance operational predictability and reduce costs through strategically positioned hubs.

TwoStep Therapeutics
Century Health
FemTherapeuticsHealthcare Digital

FemTherapeutics is building the first vertically integrated pelvic health platform for personalized, at-home care, focusing on women's health and pelvic floor support.

Neobe
Pageport

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Research briefRead more
2048 Ventures Research Investment Thesis & Core Philosophy 2048 Ventures is a thesis-driven early-stage venture capital firm based in NYC and Boston that invests exclusively in visionary founders building transformative technologies in their four core focus areas: Vertical AI, Deep Tech, Healthcare, and Biotech. The firm believes that the next generation of great companies will be built on defensi

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