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Boulder Ventures

Boulder, Colorado · Invests in US · Website

Series AB2B SaaSAI & Machine LearningDeveloper ToolsCybersecurityFintechHealthcare & BiotechEnterprise SoftwareBiotech & Life SciencesDeveloper Tools & InfrastructureSecurity & CybersecurityFintech & PaymentsInsurance

Thesis

We invest in early-stage information technology and biotechnology companies in Colorado and the Mid-Atlantic. Our philosophy is rooted in mountain guide principles: careful pattern recognition under uncertainty, patience in waiting for proper conditions, and a commitment to realized returns over paper valuations. We provide hands-on operational partnership, board-level involvement, and access to deep regional networks built over decades.

Likely not a fit for

We do not invest in consumer-facing applications without defensible moats, pure hardware plays, non-technical founding teams in IT sectors, or business models dependent on hypergrowth without sustainable unit economics.

How they invest

Lead or follow
Usually leads
Typical decision
~1 month
Warm intro
Preferred
Involvement
Takes a board seat
Fund status
Actively deploying
Assets under mgmt
$500M
Decision process
Partnership vote

Partners & team

5 contacts on file

KL

Kyle Lefkoff

General PartnerFounder & General Partner · Primary contact

+ Pitch

k•••@ho•••.com

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PR

Peter Roshko

General PartnerGeneral Partner

+ Pitch
KM

Kishen Mangat

General PartnerGeneral Partner

+ Pitch

LinkedIn profile

X profile

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JP

Jonathan Perl

General PartnerGeneral Partner

+ Pitch

j•••@bo•••.com

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MP

Matthew Paul

Platform & OpsChief Financial Officer

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Portfolio

Array BioPharmaBiotech Life Sciences

Array BioPharma focuses on developing targeted therapies for cancer and other diseases, emphasizing innovative drug discovery and development processes.

Hauser Chemical ResearchManufacturing Industrial
NeXstar PharmaceuticalsBiotech Life Sciences

NeXstar Pharmaceuticals is a company specializing in pharmaceutical products.

DharmaconBiotech Life Sciences

Dharmacon offers a range of reagents for functional genomics, specializing in RNAi and CRISPR technologies.

GenomicaHealthcare Digital

Genomica is a pioneer in molecular diagnostics and genetic identification, specializing in in-vitro diagnostics and automated solutions that adhere to high scientific and regulatory standards.

miRagen TherapeuticsBiotech Life Sciences

Miragen Therapeutics focuses on developing treatments for autoimmune diseases, known for its work in antibody discovery.

ArcherDXBiotech Life Sciences

ArcherDX provides software and databases for genomic analysis, particularly focusing on gene fusion data relevant to cancer research.

MineralysEcommerce Marketplaces

Mineralys specializes in selling collectible minerals, fossils, and artisanal jewelry made from natural stones. The company operates an online store with a wide selection of semi-precious stones and handcrafted jewelry.

StardogEnterprise Software

Stardog is a Semantic AI Platform that enables organizations to connect, integrate, and analyze data across various sources, leveraging knowledge graphs and AI technologies.

AntithesisEnterprise Software

Antithesis tests complex distributed systems. It automates end-to-end system testing and finds the unknown unknowns that traditional testing methods miss.

Synaptic EraEnterprise Software

Synaptic helps healthcare, government, and technology organizations leverage AI to compete in today's marketplace. We provide vertical AI solutions that extend Salesforce environments with purpose-built apps and AI agents.

Travel CuriousTravel Hospitality

Travel Curious offers authentic private tours led by handpicked guides, providing bespoke local experiences and avoiding crowds.

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Research briefRead more
Boulder Ventures Research Document Investment Thesis Boulder Ventures is a veteran-led venture capital firm focused exclusively on early-stage information technology and biotechnology companies in Colorado and the Mid-Atlantic regions. The firm believes in the power of local expertise, deep founder relationships built over decades, and hands-on support through the pre-investment and early growth p

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