Main Sequence Ventures
Sydney · Invests in Sydney, Australia · Website
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🔒 $•• – $••Thesis
Australian deep tech venture firm founded by national science agency CSIRO in 2017, with over $1B under management across four funds. Invests from seed to Series B in research-driven companies working on six defined challenges spanning space, decarbonisation, AI, food, healthcare and industrial productivity.
Profile drafted from public signals. Our research team reviews every firm.
Partners & team
9 contacts on file
Main Sequence Ventures in the news
Startup Daily
How former theatre director Phil Morle became a startup visionary
19 days ago
Main Sequence Promotes Alejandra Romero to Principal
1 month ago
Drone AI startup Arkeus raises $25 million as valuation skyrockets to $100 million
3 months ago
Apply for the 2026 UNSW Founders 10x Accelerator program
4 months ago
NSW startup Cauldron adds $19 million to its funding pot
5 months ago
Dash0's $110m, Advent's Salt and Stone buy, and Convene's new capital
5 months ago
The Weekly Notable Startup Funding Report: 2/23/26
6 months ago
Kasada Secures US$20 Million to Accelerate Global Expansion and Broaden Platform Offerings
7 months ago
Top 18 Venture Capital Firms in Sydney (2026)
8 months ago
Top 30 Venture Capital Firms in Australia (2026)
8 months ago
Australia-Backed Venture Firm Wants In on Critical Minerals Boom
10 months ago
TQI Exclusive: Main Sequence’s Latest Thesis Guides Quantum Bets on the Edge of Commercial Use
Mar 2025
Half of Australian universities have a spinout fund — ahead of US and Europe
Sep 2024
Samsara Eco is working to replace plastic packaging with fossil fuel-free alternatives
Jun 2024
Textiles dyeing climate tech startup Xefco raises $10.5 million Seed extension
Apr 2024
Phil Morle on everything VC Main Sequence Ventures is doing at SXSW (and some other events that caught his eye)
Oct 2023
SMH.com.au
The woman thinking about how to feed nearly 10 billion people
Jun 2023
Psychedelic biotech startup Psylo raises $5 million Seed round
Oct 2022
The big name VCs backing Aussie magic mushrooms start-up
Oct 2022
The Week in Agrifoodtech: new investments in alternative fat, Kroger buying Albertsons, Beyond Meat cuts 200 jobs
Oct 2022
Main Sequence hunts $300m for third fund
Sep 2022
EXCLUSIVE: Australia’s RapidAIM gets funding to scale real-time pest management
Mar 2021
Main Sequence Ventures’ inaugural CSIRO Innovation Fund oversubscribed, raising $232M fund for Aussie deep tech startups - SPACE & DEFENSE
Sep 2018
Main Sequence Ventures makes first investments from the CSIRO's $200 million fund, focusing on "deep tech"
Oct 2017
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