FFundraiseJet
OS Fund logo

OS Fund

Los Angeles, CA · Invests in US · Website

Thesis

Biology is programmable. We invest in visionary entrepreneurs whose platform-level science innovations rewrite operating systems across biology, materials, diagnostics, and AI. By backing founders developing programmable biology, synthetic biology, advanced materials, computational therapeutics, and biotech infrastructure, we enable the creation of breakthrough technologies that solve global challenges.

Likely not a fit for

No consumer applications without scientific depth. No non-technical founding teams. No incremental improvements. Only paradigm-shifting science backed by exceptional founders with deep domain expertise.

How they invest

Lead or follow
Leads or follows
Typical decision
~2 weeks
Warm intro
Not required
Involvement
Takes a board seat
Fund status
Actively deploying
Assets under mgmt
$250M
Decision process
Partnership vote

Partners & team

4 contacts on file

BJ

Bryan Johnson

General PartnerFounder & General Partner · Primary contact

+ Pitch

LinkedIn profile

X profile

Sign up free to unlock contact →
MG

Mark Ghobrial

PartnerPartner

+ Pitch
HO

Hayley Ossip

PrincipalPrincipal

+ Pitch
TW

Tariq Warsi

Venture PartnerVenture Partner

+ Pitch

Portfolio

Ginkgo BioworksBiotech Life Sciences

Ginkgo Bioworks is a biotechnology company that designs custom microbes for a variety of applications, including pharmaceuticals, agriculture, and industrial processes.

AtomwiseBiotech Life Sciences

Atomwise uses machine learning to discover novel, drug-like molecules for drug development, focusing on immune and inflammatory diseases.

SynthegoBiotech Life Sciences

Synthego is a biotechnology company that specializes in CRISPR gene editing and molecular diagnostics, providing innovative solutions for genetic engineering and diagnostics.

ArzedaBiotech Life Sciences

Arzeda is a protein design company that creates new designer proteins and enzymes to address challenges in food production, nutrition, and sustainable materials. They utilize Intelligent Protein Design Technology, combining physics-based design and AI to innovate across various industries.

Pivot BioAgetech Longevity

Pivot Bio develops crop nutrition technologies that harness the power of nature to deliver nitrogen to plants, enabling microbes to convert atmospheric nitrogen and provide it to crops throughout the growing season. Their solutions aim to improve profitability, predictability, safety, and sustainability for farmers.

JUST EggFood Beverage

Just Egg is a plant-based alternative to traditional eggs, offered by Justforall.com. It features vegan recipes, including scrambles and frittatas.

Verge GenomicsBiotech Life Sciences

Verge Genomics is pioneering an AI-powered drug discovery platform that utilizes human genomics and machine learning to develop new drugs for complex diseases, focusing on conditions like ALS, Parkinson's Disease, and Frontotemporal Dementia.

TruvianEnterprise Software

OpsReady is a work completion software for industrial operations, focusing on outcomes and streamlining processes through an all-in-one mobile application.

Elysium HealthHealthcare Digital

Elysium Health translates scientific advancements in aging research into accessible health products and technologies, focusing on supplements that promote healthy aging.

Catalog Technologies
LygosBiotech Life Sciences

Lygos is an industrial biotechnology company developing biobased sustainable solutions to improve everyday products. Our technology platform enables better economics and unlocks the power of organic acids specialty chemicals, enabling our partners to offer sustainable alternatives to legacy petroleum-based plastics, fragrances, home and personal care products, and more.

uBiome

Recent activity

OS Fund in the news

Similar firms

Breakout Ventures$250K–$15M

Bioscience investor translating grant-funded research into venture-scale companies, with a pipeline centered on engineering biology using robotic cloud labs and computational design for human health and planetary sustainability. The firm grew directly out of a philanthropic grants program at the Thiel Foundation that funded highly speculative science before spinning into a traditional venture fund.

KdT Ventures$500K–$5M

Writes first institutional checks ($500k–$5M) at earliest stages for compute-applied chemistry and biology ventures (therapeutics, industrial biotech, climate, materials), led by an advanced-degree scientific team.

IndieBio$500K–$525K

Early-stage accelerator for synthetic biology and life sciences that gives scientist-founders lab independence with co-located BSL-rated wet labs and extended runway via SOSV integration reserving 75% for follow-ons. The world's first startup accelerator focused specifically on synthetic biology and life sciences, created to give scientists independence as founders rather than forcing them into traditional academic or big-pharma tracks. The program runs its own large wet-lab infrastructure where portfolio companies co-locate and build in BSL-rated labs owned by the fund, while providing an unusually long runway of capital through deep integration with SOSV's fund structure that reserves 75% for follow-on rounds.

Humboldt Fund$500K–$2M

Exclusive synthetic biology investor focused on companies replacing industrial inputs with biology-based alternatives, led by a UCSF-trained PhD cell biologist offering deep research expertise and global Latin America–Europe reach.

Axial VC$100K–$5M

Invests in early-stage life sciences companies, often backing founders when they are no more than an idea.

Research briefRead more
OS Fund Research Document Investment Thesis OS Fund is a pioneering venture capital fund founded by tech entrepreneur Bryan Johnson in 2014 with a personal $•• endowment. The fund is dedicated to backing visionary entrepreneurs whose platform-level science innovations aim to "rewrite operating systems" across biology, materials, diagnostics, and artificial intelligence. OS Fund's core thesis is

Sign up free to read the full research brief →

Add OS Fund to your investor list

Sign up free to save investors, see partner contacts, and track your raise.

Sign up