Frist Cressey Ventures

Chamber is dedicated to supporting cardiology practices through technology-enabled delivery, focusing on value-based care to improve patient outcomes and practice success.

One to One Health provides relationship-based healthcare through on-site clinics and on-demand TextCare services, offering personalized and accessible medical care.

Ambience Healthcare provides an AI platform designed to streamline documentation and coding processes for healthcare providers, reducing clinician burnout and improving patient care across various specialties.

Aradigm is a benefits platform for cell and gene therapies, focused on creating sustainable access to life-saving medicines through innovative financial and delivery models.

Aspire Health offers a range of holistic health services including naturopathic medicine, occupational therapy, acupuncture, and nutrition counseling, focusing on individualized care and wellness.

Audacious Inquiry enhances healthcare through innovative technology solutions and impactful strategies that enable seamless care collaboration, resulting in improved health outcomes and operational efficiencies.

Axuall leverages real-time clinician data to transform the way industry leaders analyze, recruit, onboard, and engage their most valuable resource: clinicians.

Bicycle Health is the largest medical group in the U.S. providing Medication for Opioid Use Disorder (MOUD) treatment via telemedicine, combining clinical care, therapy, and peer support.

Blackbird Health provides virtual and in-person mental health care for children, teens, and young adults, focusing on developmental differences, mental health concerns, and behavioral issues.

CareBridge exists to enable individuals in home and community-based settings to maximize their health, independence, and quality of life.

Healthcare AI Platform for Clinical Data Management, offering solutions for clinical data abstraction, registry data capture, and real-world data insights.

CodaMetrix provides contextual coding automation solutions designed to enhance coding accuracy and efficiency for healthcare providers.

Backed by six North Carolina health systems and a major payor, they provide executive advisory access and a repeatable digital-health playbook to navigate provider/payor channels, with notable exits. The fund has built a repeatable playbook in tech-enabled healthcare services and digital health with notable exits that collectively generated roughly $100M in exit value and over $285M in follow-on capital since 2021.

Co-creates and incubates healthcare startups with payers, providers and health systems—using partner data, workflows and distribution to pressure-test products and secure anchor-customer integration.

Early-stage healthcare investor with a concentrated, thematically coherent digital-health portfolio (infrastructure, AI diagnostics, virtual specialty care, women's health) that partners closely and prioritizes underrepresented founders, diversifying cap tables.

Venture studio and fund that co-incubates with LifePoint executives, giving startups direct access to a $50B+ health system for pilot deployment, real-world validation, and underserved population focus.

Define Ventures runs a free AI Fellows program connecting founders to former Fortune 100 health CEOs, tailored go-to-market training, enduring partner mentorship, and network of payers, providers, employers, and life-science companies.